The BNIP3 Polyclonal Antibody (CAB15032) is a valuable tool for researchers studying the BNIP3 protein, which plays a pivotal role in cellular processes such as apoptosis and autophagy. This antibody, produced in rabbits, is highly specific to human samples and is ideal for use in Western blot applications. By binding to the BNIP3 protein, this antibody enables researchers to detect and analyze BNIP3 expression in various cell types, making it a valuable asset in studies related to cell death mechanisms and cancer research.BNIP3 is a key regulator of programmed cell death, playing a crucial role in maintaining cellular homeostasis and responding to various stress stimuli.
Dysregulation of BNIP3 expression has been implicated in the pathogenesis of cancer, cardiovascular diseases, and neurodegenerative disorders, underscoring the importance of studying this protein in various disease contexts. By understanding the role of BNIP3, researchers can uncover new therapeutic targets and strategies for combating diseases associated with aberrant cell death processes.
Product Name:
BNIP3 Rabbit Polyclonal Antibody
SKU:
CAB15032
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human BNIP3 (NP_004043.3).
This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.
Purification Method:
Affinity purification
Gene ID:
664
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of U2OS cells using BNIP3 antibody (CAB15032) at dilution of 1:100. Blue: DAPI for nuclear staining.
