The BNIP1 Polyclonal Antibody (CAB7263) is a valuable tool for researchers studying BNIP1, a protein involved in apoptosis, mitochondrial dysfunction, and autophagy. This antibody is produced in rabbits and exhibits high reactivity towards human samples, making it an excellent choice for Western blot applications. By binding specifically to BNIP1, this antibody allows for the detection and analysis of BNIP1 protein levels in a variety of cell types.BNIP1 is a key player in cellular processes such as programmed cell death and cellular energy metabolism, highlighting its importance in the field of cancer research and neurodegenerative diseases.
Its involvement in regulating mitochondrial function and cell survival makes it a promising target for therapeutic interventions aimed at controlling cell death pathways and promoting cell survival.With its ability to specifically detect BNIP1 protein levels, the CAB7263 antibody is a valuable tool for researchers interested in unraveling the molecular mechanisms underlying apoptosis and autophagy, and its implications in disease pathology. Investigating BNIP1 function may provide insights into potential therapeutic strategies for diseases associated with dysregulated cell death pathways.
Product Name:
BNIP1 Rabbit Polyclonal Antibody
SKU:
CAB7263
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human BNIP1 (NP_001196.2).
Endoplasmic reticulum membrane, Mitochondrion, Single-pass type IV membrane protein.
Calculated MW:
26kDa
Observed MW:
26kDa
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. In addition, this protein is involved in vesicle transport into the endoplasmic reticulum. Alternative splicing of this gene results in four protein products with identical N- and C-termini.
Purification Method:
Affinity purification
Gene ID:
662
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using BNIP1 Antibody (CAB7263) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
