BMPR2 Rabbit Polyclonal Antibody (CAB5666)
- SKU:
- CAB5666
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | BMPR2 Rabbit Polyclonal Antibody |
SKU: | CAB5666 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-150 of human BMPR2 (NP_001195.2). |
Sequence: | SQNQ ERLC AFKD PYQQ DLGI GESR ISHE NGTI LCSK GSTC YGLW EKSK GDIN LVKQ GCWS HIGD PQEC HYEE CVVT TTPP SIQN GTYR FCCC STDL CNVN FTEN FPPP DTTP LSPP HSFN RDET |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | BMR2; PPH1; BMPR3; BRK-3; POVD1; T-ALK; BMPR-II; BMPR2 |
Positive Sample: | HeLa,NIH/3T3,PC-12 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 115kDa |
Observed MW: | 100kDa |
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.
Purification Method: | Affinity purification |
Gene ID: | 659 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |