BMPR2 Rabbit Polyclonal Antibody (CAB16232)
- SKU:
- CAB16232
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | BMPR2 Rabbit Polyclonal Antibody |
SKU: | CAB16232 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 739-1038 of human BMPR2 (NP_001195.2). |
Sequence: | PTQI YPLP KQQN LPKR PTSL PLNT KNST KEPR LKFG SKHK SNLK QVET GVAK MNTI NAAE PHVV TVTM NGVA GRNH SVNS HAAT TQYA NGTV LSGQ TTNI VTHR AQEM LQNQ FIGE DTRL NINS SPDE HEPL LRRE QQAG HDEG VLDR LVDR RERP LEGG RTNS NNNN SNPC SEQD VLAQ GVPS TAAD PGPS KPRR AQRP NSLD LSAT NVLD GSSI QIGE STQD GKSG SGEK IKKR VKTP YSLK RWRP STWV ISTE SLDC EVNN NGSN RAVH SKSS TAVY LAEG GTAT TMVS KDIG MNCL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:1000 |
Synonyms: | BMR2; PPH1; BMPR3; BRK-3; POVD1; T-ALK; BMPR-II; BMPR2 |
Positive Sample: | MCF7,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 115kDa |
Observed MW: | 115kDa |
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.
Purification Method: | Affinity purification |
Gene ID: | 659 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |