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BMPR1A Rabbit Polyclonal Antibody (CAB1816)

SKU:
CAB1816
Product Type:
Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:BMPR1A Rabbit Polyclonal Antibody
SKU:CAB1816
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-200 of human BMPR1A (NP_004320.2).
Sequence:QNLD SMLH GTGM KSDS DQKK SENG VTLA PEDT LPFL KCYC SGHC PDDA INNT CITN GHCF AIIE EDDQ GETT LASG CMKY EGSD FQCK DSPK AQLR RTIE CCRT NLCN QYLQ PTLP PVVI GPFF DGSI RWLV LLIS MAVC IIAM IIFS SCFC YKHY CKSI SSRR RYNR DLEQ DEAF I
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:ALK3; SKR5; ALK-3; CD292; ACVRLK3; BMPR-1A; 10q23del; BMPR1A
Positive Sample:293T,A-549,MCF7,Mouse brain,Rat brain
Conjugate:Unconjugated
Cellular Localization:Membrane, Single-pass type I membrane protein.
Calculated MW:60kDa
Observed MW:60kDa

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Purification Method:Affinity purification
Gene ID:657
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using BMPR1A Rabbit pAb (CAB1816) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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