The BMP8B/BMP8A Antibody (PACO05087) is a valuable tool for researchers studying the bone morphogenetic protein (BMP) family members BMP8B and BMP8A. This polyclonal antibody is raised in rabbits and has been validated for use in various applications, including Western blot and immunohistochemistry.BMP8B and BMP8A are members of the BMP family, which plays a crucial role in various biological processes, including development, cell differentiation, and bone formation. The BMP8B/BMP8A Antibody specifically binds to these proteins, allowing for their detection and analysis in different cell types and tissues.
Research into BMP8B and BMP8A has shown their involvement in various physiological and pathological processes, making them potential targets for therapeutic interventions. By using the BMP8B/BMP8A Antibody, researchers can further elucidate the roles of these proteins in signaling pathways and disease progression, particularly in the fields of developmental biology and cancer research.
Antibody Name:
BMP8B/BMP8A Antibody (PACO05087)
Antibody SKU:
PACO05087
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:40000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human BMP-8.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
BMP8B; BMP8; Bone morphogenetic protein 8B; BMP-8; BMP-8B; Osteogenic protein 2; OP-2; BMP8A; Bone morphogenetic protein 8A; BMP-8A
UniProt Protein Function:
BMP8B: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Belongs to the TGF-beta family.Protein type: Secreted; Secreted, signal peptide; CytokineChromosomal Location of Human Ortholog: 1p35-p32Cellular Component: extracellular spaceMolecular Function: cytokine activity; growth factor activity; transforming growth factor beta receptor bindingBiological Process: BMP signaling pathway; cartilage development; cell development; growth; ossification; regulation of apoptosis; regulation of MAPKKK cascade; skeletal development
