The BMP8B Polyclonal Antibody (PACO00471) is a valuable tool for researchers studying BMP8B, a member of the bone morphogenetic protein (BMP) family known for its role in various biological processes. This antibody is produced in rabbits and specifically targets human samples, making it highly reliable for use in Western blot applications. By binding to the BMP8B protein, this antibody allows for accurate detection and analysis in a wide range of cell types, making it an essential component for studies in developmental biology and tissue regeneration.
BMP8B is a key player in regulating cell growth, differentiation, and apoptosis, making it a promising target for research into various diseases and disorders. Its involvement in important physiological processes underscores its potential therapeutic applications in regenerative medicine and tissue engineering. By investigating the function of BMP8B, researchers can gain valuable insights into its role in disease pathogenesis and potentially identify new therapeutic strategies for conditions such as bone disorders and cancer.
Antibody Name:
BMP8B Antibody
Antibody SKU:
PACO00471
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human BMP-8B.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
BMP8B; BMP8; Bone morphogenetic protein 8B; BMP-8; BMP-8B; Osteogenic protein 2; OP-2
UniProt Protein Function:
BMP8B: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Belongs to the TGF-beta family.Protein type: Secreted; Secreted, signal peptide; CytokineChromosomal Location of Human Ortholog: 1p35-p32Cellular Component: extracellular spaceMolecular Function: cytokine activity; growth factor activity; transforming growth factor beta receptor bindingBiological Process: BMP signaling pathway; cartilage development; cell development; growth; ossification; regulation of apoptosis; regulation of MAPKKK cascade; skeletal development
