The BMP8A Polyclonal Antibody (PACO2006) is a vital tool for research involving BMP8A, a member of the bone morphogenetic protein (BMP) family known for its role in regulating various cellular processes, including bone formation and adipogenesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the BMP8A protein, researchers can accurately detect and analyze its expression in a range of cell types, making it well-suited for studies in developmental biology and metabolic diseases.
BMP8A is a key player in the signaling pathways that control cell differentiation and tissue development, with implications for skeletal development, energy metabolism, and thermoregulation. Its involvement in these processes positions it as a promising target for investigations into conditions such as osteoporosis, obesity, and metabolic disorders. Uncovering the mechanisms by which BMP8A influences cellular functions is essential for advancing our understanding of these diseases and paving the way for potential therapeutic interventions.
Antibody Name:
BMP8A Antibody
Antibody SKU:
PACO02006
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the Internal region of human BMP-8A.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
BMP8A; Bone morphogenetic protein 8A; BMP-8A
UniProt Protein Function:
BMP8A: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Belongs to the TGF-beta family.Protein type: Cytokine; Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 1p34.3Cellular Component: extracellular spaceMolecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor bindingBiological Process: BMP signaling pathway; regulation of apoptosis; ossification; diet induced thermogenesis; regulation of MAPKKK cascade; cartilage development; cell development; growth; negative regulation of insulin secretion
