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BMP7 Monoclonal Antibody [P4E7AT] (CPAB0059)

SKU:
CPAB0059
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
P4E7AT
Applications:
WB
ELISA
$179
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Description

system_update_alt Datasheet

BMP7 Monoclonal Antibody [P4E7AT] (CPAB0059)

The BMP7 Polyclonal Antibody (CPAB0059) is a powerful tool for researchers studying Bone Morphogenetic Protein 7 (BMP7), a member of the transforming growth factor-beta superfamily that plays a crucial role in regulating bone and cartilage development. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards BMP7 in human samples, making it an essential reagent for Western blot analysis.BMP7 is a key signaling molecule involved in cell differentiation, proliferation, and apoptosis, making it a promising target for therapeutic interventions in orthopedic and regenerative medicine. The BMP7 Polyclonal Antibody enables precise detection and quantification of BMP7 levels in various cell types, providing valuable insights into its biological function and potential applications in tissue engineering and bone regeneration studies.

With its ability to specifically recognize and bind to BMP7, this antibody is a valuable tool for elucidating the mechanisms underlying bone and cartilage development, as well as for exploring the therapeutic potential of BMP7 in treating musculoskeletal disorders and injuries. Researchers in the fields of developmental biology, regenerative medicine, and orthopedics will find the BMP7 Polyclonal Antibody indispensable for their studies.

Product Name:BMP7 Antibody
Product Sku:CPAB0059
Size:5μg
Host Species:Mouse
Immunogen:Anti-human BMP7 mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with Recombinant human BMP7 amino acids 293-431 purified from Ecoli.
Clone:P4E7AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:BMP7 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
Synonyms:Osteogenic Protein 1, OP-1, BMP-7.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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