BMP6 Rabbit Monoclonal Antibody (CAB4538)
- SKU:
- CAB4538
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- VGR
- VGR1
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | BMP6 Rabbit Monoclonal Antibody |
SKU: | CAB4538 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human BMP6 (NP_001709.1). |
Sequence: | DGPY DKQP FMVA FFKV SEVH VRTT RSAS SRRR QQSR NRST QSQD VARV SSAS DYNS SELK TACR KHEL YVSF QDLG WQDW IIAP KGYA ANYC DGEC SFPL N |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | IO; VGR; VGR1; BMP6 |
Positive Sample: | U-2 OS,293T,A549,Mouse lung,Mouse kidney,Mouse heart,Rat lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted |
Calculated MW: | 57kDa |
Observed MW: | 42kDa |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients.
Purification Method: | Affinity purification |
Gene ID: | 654 |
Clone Number: | ARC1025 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |