The BMP6 Rabbit Monoclonal Antibody (CAB4538) is a cutting-edge research tool specifically designed for the detection and analysis of Bone Morphogenetic Protein 6 (BMP6) in various biological samples. This antibody, produced in rabbits, is highly reactive and has been validated for use in Western blot applications.BMP6 is a multifunctional cytokine belonging to the TGF-beta superfamily, playing a crucial role in cell differentiation, proliferation, and apoptosis. It is involved in skeletal development, iron metabolism, and inflammation, making it a key player in various biological processes. The BMP6 Rabbit Monoclonal Antibody enables researchers to study the expression and function of BMP6 in different cell types and tissues, making it an invaluable tool for studies in developmental biology, regenerative medicine, and disease research.
By targeting BMP6, researchers can deepen their understanding of the molecular mechanisms underlying skeletal disorders, iron metabolism disorders, and inflammatory diseases. The BMP6 Rabbit Monoclonal Antibody is essential for investigating the role of BMP6 in these pathological conditions, paving the way for the development of innovative therapeutic strategies targeting BMP6 signaling pathways.
Product Name:
BMP6 Rabbit Monoclonal Antibody
SKU:
CAB4538
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human BMP6 (NP_001709.1).
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients.
Purification Method:
Affinity purification
Gene ID:
654
Clone Number:
ARC1025
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using BMP6 Rabbit mAb (CAB4538) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
