BMP6 Rabbit Polyclonal Antibody (CAB8333)
- SKU:
- CAB8333
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | BMP6 Rabbit Polyclonal Antibody |
SKU: | CAB8333 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 375-513 of human BMP6 (NP_001709.1). |
Sequence: | SASS RRRQ QSRN RSTQ SQDV ARVS SASD YNSS ELKT ACRK HELY VSFQ DLGW QDWI IAPK GYAA NYCD GECS FPLN AHMN ATNH AIVQ TLVH LMNP EYVP KPCC APTK LNAI SVLY FDDN SNVI LKKY RNMV VRAC GCH |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | IO; VGR; VGR1; BMP6 |
Positive Sample: | DU145,Mouse lung,Mouse kidney,Mouse heart,Rat brain,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 57kDa |
Observed MW: | 57kDa |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients.
Purification Method: | Affinity purification |
Gene ID: | 654 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |