BMP5 Rabbit Polyclonal Antibody (CAB8401)
- SKU:
- CAB8401
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | BMP5 Rabbit Polyclonal Antibody |
SKU: | CAB8401 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 317-454 of human BMP5 (NP_066551.1). |
Sequence: | AANK RKNQ NRNK SSSH QDSS RMSS VGDY NTSE QKQA CKKH ELYV SFRD LGWQ DWII APEG YAAF YCDG ECSF PLNA HMNA TNHA IVQT LVHL MFPD HVPK PCCA PTKL NAIS VLYF DDSS NVIL KKYR NMVV RSCG CH |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 |
Synonyms: | BMP5 |
Positive Sample: | H460,LO2,SW620,293T,mouse liver,mouse small intestine,mouse skeletal muscle,rat lung,rat liver,NCI-H460,Mouse lung,Mouse liver,Mouse small intestine |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 52kDa |
Observed MW: | 52kDa |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers. This gene encodes distinct protein isoforms that may be similarly proteolytically processed.
Purification Method: | Affinity purification |
Gene ID: | 653 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |