The BMP4 Rabbit Monoclonal Antibody is a cutting-edge tool for researchers investigating BMP4, a key signaling molecule involved in various cellular processes including development, differentiation, and tissue homeostasis. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards BMP4 in human samples, making it an ideal choice for Western blotting and immunohistochemistry experiments.By targeting the BMP4 protein, this antibody enables precise detection and analysis of BMP4 expression in different cell types, providing valuable insights into its role in normal physiology and disease development.
With its superior performance and reliability, this antibody is a valuable asset for studies in developmental biology, tissue engineering, and regenerative medicine.Given the diverse functions of BMP4 in various biological processes, understanding its mechanisms of action is crucial for advancing research in areas such as stem cell biology, organogenesis, and therapeutic interventions. The BMP4 Rabbit Monoclonal Antibody offers researchers a powerful tool to unravel the intricate functions of BMP4 and pave the way for innovative scientific discoveries in the field of molecular biology.
Product Name:
BMP4 Rabbit Monoclonal Antibody
SKU:
CAB11405
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 309-408 of human BMP4 (P12644).
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.
Purification Method:
Affinity purification
Gene ID:
652
Clone Number:
ARC0587
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using BMP4 Rabbit mAb (CAB11405) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
