BMP4 Rabbit Monoclonal Antibody (CAB11405)
- SKU:
- CAB11405
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | BMP4 Rabbit Monoclonal Antibody |
SKU: | CAB11405 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 309-408 of human BMP4 (P12644). |
Sequence: | RRHS LYVD FSDV GWND WIVA PPGY QAFY CHGD CPFP LADH LNST NHAI VQTL VNSV NSSI PKAC CVPT ELSA ISML YLDE YDKV VLKN YQEM VVEG CGCR |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | ZYME; BMP2B; OFC11; BMP2B1; MCOPS6; BMP4 |
Positive Sample: | 293T,A-549,PC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 47kDa |
Observed MW: | 47kDa |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.
Purification Method: | Affinity purification |
Gene ID: | 652 |
Clone Number: | ARC0587 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |