The BMP4 Polyclonal Antibody (CAB1565) is a valuable tool for researchers studying BMP4, a member of the bone morphogenetic protein family that plays a key role in various biological processes including embryogenesis, cell differentiation, and tissue regeneration. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.BMP4 is involved in the development and maintenance of various tissues and organs, making it a crucial factor in development and disease. By targeting the BMP4 protein, this antibody allows for the detection and analysis of BMP4 levels in different cell types, making it ideal for research in developmental biology, regenerative medicine, and cancer biology.
The BMP4 Polyclonal Antibody is a valuable resource for researchers looking to investigate the role of BMP4 in various physiological and pathological processes. By better understanding the function of BMP4, scientists can uncover new insights into embryonic development, tissue regeneration, and diseases such as cancer and osteoporosis.
Product Name:
BMP4 Rabbit Polyclonal Antibody
SKU:
CAB1565
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human BMP4 (NP_001193.2).
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.
Purification Method:
Affinity purification
Gene ID:
652
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using BMP4 antibody (CAB1565) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
