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BMP3 Rabbit Polyclonal Antibody (CAB6877)

SKU:
CAB6877
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 10 Anti-BMP3 Antibody CAB6877
  • Cell Biology Antibodies 10 Anti-BMP3 Antibody CAB6877
  • Cell Biology Antibodies 10 Anti-BMP3 Antibody CAB6877
  • Cell Biology Antibodies 10 Anti-BMP3 Antibody CAB6877
  • Cell Biology Antibodies 10 Anti-BMP3 Antibody CAB6877
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:BMP3 Rabbit Polyclonal Antibody
SKU:CAB6877
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 243-472 of human BMP3 (NP_001192.2).
Sequence:YAND AAIS EPES VVSS LQGH RNFP TGTV PKWD SHIR AALS IERR KKRS TGVL LPLQ NNEL PGAE YQYK KDEV WEER KPYK TLQA QAPE KSKN KKKQ RKGP HRKS QTLQ FDEQ TLKK ARRK QWIE PRNC ARRY LKVD FADI GWSE WIIS PKSF DAYY CSGA CQFP MPKS LKPS NHAT IQSI VRAV GVVP GIPE PCCV PEKM SSLS ILFF DENK NVVL KVYP NMTV ESCA CR
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:100 - 1:200
Synonyms:BMP-3A; BMP3
Positive Sample:SW480,Mouse ovary,Mouse lung
Conjugate:Unconjugated
Cellular Localization:Secreted.
Calculated MW:53kDa
Observed MW:53kDa

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands.

Purification Method:Affinity purification
Gene ID:651
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using BMP3 Rabbit pAb (CAB6877) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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