BMP2 Rabbit Polyclonal Antibody (CAB12781)
- SKU:
- CAB12781
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | BMP2 Rabbit Polyclonal Antibody |
SKU: | CAB12781 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human BMP2 (NP_001191.1). |
Sequence: | MVAG TRCL LALL LPQV LLGG AAGL VPEL GRRK FAAA SSGR PSSQ PSDE VLSE FELR LLSM FGLK QRPT PSRD AVVP PYML DLYR RHSG QPGS PAPD HRLE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | BDA2; BMP2A; SSFSC; SSFSC1; BMP2 |
Positive Sample: | HT-29,Mouse spleen,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 45kDa |
Observed MW: | 42kDa |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
Purification Method: | Affinity purification |
Gene ID: | 650 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |