The BMP2 Polyclonal Antibody (CAB0231) from AssayGenie is a cutting-edge tool for researchers studying Bone Morphogenetic Protein 2 (BMP2), a key player in bone and cartilage formation. This antibody, produced in rabbits, is highly specific to human samples and has been rigorously tested for its performance in Western blot applications.BMP2 is a critical growth factor in the TGF-beta superfamily, known for its role in osteogenesis and chondrogenesis. By targeting BMP2, researchers can study the mechanisms of bone development, tissue regeneration, and potential therapeutic interventions for bone-related disorders.
With its high reactivity and specificity, the BMP2 Polyclonal Antibody is a valuable asset for investigations in bone biology, regenerative medicine, and musculoskeletal research. By enabling precise detection and analysis of BMP2 protein expression, this antibody facilitates deeper insights into the molecular pathways involved in skeletal development and repair processes.
Product Name:
BMP2 Rabbit Polyclonal Antibody
SKU:
CAB0231
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 283-396 of human BMP2 (NP_001191.1).
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
Purification Method:
Affinity purification
Gene ID:
650
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Hep G2 cells using BMP2 Rabbit pAb(CAB0231) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
