The BMP1 Polyclonal Antibody (CAB16353) is a valuable tool for researchers studying bone morphogenetic protein 1 (BMP1), a key player in bone formation and development. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the BMP1 protein, this antibody enables accurate detection and analysis in various cell types, making it an ideal choice for studies in bone biology, regenerative medicine, and developmental biology.
BMP1 is a metalloprotease involved in the processing of extracellular matrix components and the activation of various growth factors and signaling molecules. Its crucial role in bone development and mineralization makes it a promising target for research into skeletal disorders, osteoporosis, and bone regeneration therapies. Understanding the function and regulation of BMP1 is essential for advancing our knowledge of bone biology and developing novel treatments for bone-related conditions.
Product Name:
BMP1 Rabbit Polyclonal Antibody
SKU:
CAB16353
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 725-986 of human BMP1 (NP_006120.1).
This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.
Purification Method:
Affinity purification
Gene ID:
649
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunofluorescence analysis of HeLa cells using BMP1 Rabbit pAb (CAB16353) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.