Bmi1 Rabbit Monoclonal Antibody (CAB17914)
- SKU:
- CAB17914
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Bmi1 Rabbit Monoclonal Antibody |
SKU: | CAB17914 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 227-326 of human Bmi1 (P35226). |
Sequence: | VRPT CKRM KISH QRDG LTNA GELE SDSG SDKA NSPA GGIP STSS CLPS PSTP VQSP HPQF PHIS STMN GTSN SPSG NHQS SFAN RPRK SSVN GSSA TSSG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | PCGF4; RNF51; FLVI2/BMI1; flvi-2/bmi-1; Bmi1 |
Positive Sample: | K-562,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus |
Calculated MW: | 37kDa |
Observed MW: | 40kDa |
This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.
Purification Method: | Affinity purification |
Gene ID: | 648 |
Clone Number: | ARC0376 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |