BMF Rabbit Polyclonal Antibody (CAB5796)
- SKU:
- CAB5796
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | BMF Rabbit Polyclonal Antibody |
SKU: | CAB5796 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human BMF (NP_277038.1). |
Sequence: | MEPS QCVE ELED DVFQ PEDG EPVT QPGS LLSA DLFA QSLL DCPL SRLQ LFPL THCC GPGL RPTS QEDK ATQT LSPA SPSQ GVML PCGV TEEP QRLF YGNA GYRL PLPA SFPA VLPI GEQP PEGQ WQHQ AEVQ IARK LQCI ADQF HRLH VQQH QQNQ NRVW WQIL LFLH NLAL NGEE NRNG AGPR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | BMF |
Positive Sample: | U-937,SW480,Mouse liver,Mouse lung,Mouse spleen,Mouse ovary,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, mitochondrial outer membrane, plasma membrane |
Calculated MW: | 21kDa |
Observed MW: | 21kDa |
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 90427 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |