The BLOC1S2 Polyclonal Antibody (CAB8007) is a valuable tool for researchers studying BLOC1S2, a key protein involved in intracellular protein trafficking and organelle biogenesis. This antibody, generated in rabbits, is specifically designed to target BLOC1S2 in human samples and has been validated for use in Western blot applications. Its high reactivity allows for accurate detection and analysis of BLOC1S2 in various cell types, making it an essential component for studies in cell biology and molecular biology.BLOC1S2 plays a crucial role in regulating the formation and function of lysosome-related organelles, making it a potential target for investigating lysosomal storage disorders and other diseases associated with lysosomal dysfunction.
By understanding the function and regulation of BLOC1S2, researchers can gain insights into the underlying mechanisms of these diseases and potentially identify new therapeutic targets for intervention. The BLOC1S2 Polyclonal Antibody is a valuable tool for advancing our understanding of BLOC1S2's role in cellular processes and disease pathology.
Product Name:
BLOC1S2 Rabbit Polyclonal Antibody
SKU:
CAB8007
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 44-142 of human BLOC1S2 (NP_776170.2).
This gene encodes a protein with multiple functions. The encoded protein has been found in association with the centrosome, shown to co-localize with gamma-tubulin, and also found to be one of the proteins in the BLOC-1 complex which functions in the formation of lysosome-related organelles. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
282991
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using BLOC1S2 antibody (CAB8007) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 30s.