BIRC7 Rabbit Polyclonal Antibody (CAB5736)
- SKU:
- CAB5736
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | BIRC7 Rabbit Polyclonal Antibody |
SKU: | CAB5736 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human BIRC7 (NP_647478.1). |
Sequence: | MGPK DSAK CLHR GPQP SHWA AGDG PTQE RCGP RSLG SPVL GLDT CRAW DHVD GQIL GQLR PLTE EEEE EGAG ATLS RGPA FPGM GSEE LRLA SFYD WPLT AEVP PELL AAAG FFHT GHQD KVRC FFCY GGLQ SWKR GDDP WTEH AKWF PSCQ FLLR SKGR DFVH SVQE THSQ LLGS WDPW EEPE DAAP VAPS VPAS GYPE LPTP RREV QSES AQEP GGVS PAEA QRAW WVLE PPGA RDVE AQLR RLQE ERTC KVCL DRAV SIVF V |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | KIAP; LIVIN; MLIAP; RNF50; ML-IAP; BIRC7 |
Positive Sample: | MCF7,HL-60,HepG2,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Golgi apparatus, Nucleus. |
Calculated MW: | 33kDa |
Observed MW: | 33kDa |
This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants
Purification Method: | Affinity purification |
Gene ID: | 79444 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |