The BIRC7 Polyclonal Antibody (CAB5736) is a valuable tool for researchers studying BIRC7, a member of the inhibitor of apoptosis proteins (IAP) family known for its role in regulating cell death and survival pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.By targeting the BIRC7 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for investigations in cancer biology and apoptosis research.
BIRC7 is involved in the regulation of apoptosis, making it a crucial factor in cell survival and death processes.The BIRC7 Polyclonal Antibody offers researchers a reliable way to examine the functions and mechanisms of BIRC7, shedding light on its involvement in disease states such as cancer and neurodegenerative disorders. Understanding the role of BIRC7 may provide insights into potential therapeutic strategies targeting abnormal cell death pathways.
Product Name:
BIRC7 Rabbit Polyclonal Antibody
SKU:
CAB5736
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human BIRC7 (NP_647478.1).
This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants
Purification Method:
Affinity purification
Gene ID:
79444
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using BIRC7 antibody (CAB5736) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
