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Survivin Rabbit Polyclonal Antibody (CAB1551)

SKU:
CAB1551
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
  • Cell Death Antibodies 1 Anti-Survivin Antibody CAB1551
  • Cell Death Antibodies 1 Anti-Survivin Antibody CAB1551
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Survivin Rabbit Polyclonal Antibody
SKU:CAB1551
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human Survivin (NP_001159.2).
Sequence:MGAP TLPP AWQP FLKD HRIS TFKN WPFL EGCA CTPE RMAE AGFI HCPT ENEP DLAQ CFFC FKEL EGWE PDDD PIEE HKKH SSGC AFLS VKKQ FEEL TLGE FLKL DRER AKNK IAKE TNNK KKEF EETA EKVR RAIE QLAA MD
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:100 - 1:500 IHC-P,1:50 - 1:200
Synonyms:API4; EPR-1; Survivin
Positive Sample:HeLa,293F,Jurkat
Conjugate:Unconjugated
Cellular Localization:Chromosome, Cytoplasm, Midbody, Nucleus, centromere, cytoskeleton, kinetochore, spindle.
Calculated MW:16kDa
Observed MW:16kDa

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:332
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using Survivin Rabbit pAb (CAB1551) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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