The BIRC3 Polyclonal Antibody (CAB0833) is a valuable tool for researchers studying BIRC3, a key regulator of cell survival and apoptosis. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the BIRC3 protein, this antibody allows for precise detection and analysis of BIRC3 expression in a variety of cell types.BIRC3, also known as cIAP2, is a crucial player in cell signaling pathways that control apoptosis and inflammation. Dysregulation of BIRC3 has been implicated in various diseases, including cancer and autoimmune disorders.
Therefore, studying the function of BIRC3 using this polyclonal antibody can provide valuable insights into the mechanisms underlying these diseases and potentially lead to the development of targeted therapies.Overall, the BIRC3 Polyclonal Antibody (CAB0833) is a reliable and effective tool for researchers interested in unraveling the role of BIRC3 in health and disease. Its high specificity and sensitivity make it an ideal choice for studies in the fields of cell biology, oncology, and immunology.
Product Name:
cIAP2 Rabbit Polyclonal Antibody
SKU:
CAB0833
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-130 of human cIAP2 (NP_001156.1).
This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
Purification Method:
Affinity purification
Gene ID:
330
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using cIAP2 Rabbit pAb (CAB0833) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
