Description
Product Name: | Biotinylated Recombinant Human Tyrosine-protein kinase receptor UFO/Axl Protein |
SKU: | RPCB0048 |
Size: | 100µg |
Tag: | C-His&Avi |
Reactivity: | Human |
Protein Description: | High quality, high purity and low endotoxin recombinant Biotinylated Recombinant Human Tyrosine-protein kinase receptor UFO/Axl Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
Endotoxin: | < 1 EU/μg of the protein by LAL method. |
Purity: | > 95% by Tris-Bis PAGE;> 95% by SEC-HPLC |
Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
Gene ID: | 558 |
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.
Storage: | Store at -20℃. Store the lyophilized protein at -20℃ to -80℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
Reconstitution: | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
Swiss-Prot: | P30530 |