Biotinylated Recombinant Human Siglec-10 (R119A) Protein (RPCB0108)
- SKU:
- RPCB0108
- Size:
- 100µg
- Tag:
- C-His&Avi
- Reactivity:
- Human
Frequently bought together:
Description
| Product Name: | Biotinylated Recombinant Human Siglec-10 (R119A) Protein |
| SKU: | RPCB0108 |
| Size: | 100µg |
| Tag: | C-His&Avi |
| Reactivity: | Human |
| Protein Description: | High quality, high purity and low endotoxin recombinant Biotinylated Recombinant Human Siglec-10 (R119A) Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | < 1 EU/μg of the protein by LAL method. |
| Purity: | > 95% by Tris-Bis PAGE;> 95% by SEC-HPLC |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of 20 mM Tirs 150 mM NaCl, 200 mM L-arginine, pH 8.0. |
| Gene ID: | 89790 |
Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.
| Storage: | Store at -20℃. Store the lyophilized protein at -20℃ to -80℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | Q96LC7-1 |
 | Biotinylated Human Siglec-10 (R119A) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
 | The purity of Biotinylated Human Siglec-10 (R119A) is greater than 95% as determined by SEC-HPLC. |
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