Biotinylated Recombinant Human LMP2 (HLA-A*02:01) Complex Protein (RPCB1799)
- SKU:
- RPCB1799
- Size:
- 100µg
- Tag:
- C-His&Avi
- Reactivity:
- Human
- Expression Host:
- HEK293 cells
Frequently bought together:
Description
Product Name: | Biotinylated Recombinant Human LMP2 (HLA-A*02:01) Complex Protein |
SKU: | RPCB1799 |
Size: | 100µg |
Tag: | C-His&Avi |
Reactivity: | Human |
Expression Host: | HEK293 cells |
Protein Description: | High quality, high purity and low endotoxin recombinant Biotinylated Recombinant Human LMP2 (HLA-A*02:01) Complex Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
Endotoxin: | Less than 1EU per μg by the LAL method. |
Purity: | > 95% as determined by Tris-Bis PAGEï¼›> 95% as determined by HPLC |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of malignant tumors that highly express LMP2.
Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
Reconstitution: | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
Swiss-Prot: | A0A140T913(HLA-A*02:01)&P61769(B2M)&CLGGLLTMV |