Biotinylated Recombinant Human FLT-3/FLK-2/CD135 Protein (RPCB0624)
- SKU:
- RPCB0624
- Size:
- 100µg
- Tag:
- C-His&Avi
- Reactivity:
- Human
Description
| Product Name: | Biotinylated Recombinant Human FLT-3/FLK-2/CD135 Protein |
| SKU: | RPCB0624 |
| Size: | 100µg |
| Tag: | C-His&Avi |
| Reactivity: | Human |
| Protein Description: | High quality, high purity and low endotoxin recombinant Biotinylated Recombinant Human FLT-3/FLK-2/CD135 Protein , tested reactivity in CHO cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | < 1 EU/μg of the protein by LAL method |
| Purity: | > 95% by SDS-PAGEï¼›> 95% by HPLC |
| Formulation: | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Gene ID: | 2322 |
The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1.
| Storage: | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
| Swiss-Prot: | P36888-1 |
 | Biotinylated Human FLT3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
 | The purity of Biotinylated Human FLT3 is greater than 95% as determined by SEC-HPLC. |
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