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Biotinylated Recombinant Human ALCAM/CD166 Protein (Primary Amine Labeling) (RPCB0668)

SKU:
RPCB0668
Size:
100µg
Tag:
C-His
Reactivity:
Human
€779
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Description

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Product Name:Biotinylated Recombinant Human ALCAM/CD166 Protein (Primary Amine Labeling)
SKU:RPCB0668
Size:100µg
Tag:C-His
Reactivity:Human
Protein Description:High quality, high purity and low endotoxin recombinant Biotinylated Recombinant Human ALCAM/CD166 Protein (Primary Amine Labeling) , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:< 1 EU/μg of the protein by LAL method
Purity:> 95% by SDS-PAGE
Formulation:Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Gene ID:214

Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:Q13740-1
Product ImageBiotinylated Human ALCAM (Primary Amine Labeling) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Product ImageImmobilized Anti-ALCAM Antibody, hFc Tag at 5 μg/mL (100 μL/well) on the plate. Dose response curve for Biotinylated Human ALCAM, His Tag with the EC50 of 1.6 μg/mL determined by ELISA.

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