null

Biotinylated Human CD4 full length protein-synthetic nanodisc (HDFP759)

SKU:
HDFP759
Size:
10μg
Target:
CD4
Tag:
Biotinylated, C-Flag&Avi Tag
Expression Host:
HEK293
Conjugate:
Biotinylated
$1,835
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Biotinylated Nanodisc Human CD4 Protein
SKU:HDFP759
Size:10μg
Target:CD4
Tag:Biotinylated, C-Flag&Avi Tag
Expression Host:HEK293
Conjugate:Biotinylated
Synonyms:T4; IMD79; Leu-3; OKT4D; CD4mut
Protein Families:Transmembrane.
Protein Description:Biotinylated Human CD4 full length protein-synthetic nanodisc
Protein Pathways:Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway.
Molecular Weight:The human full length CD4 Protein has a MW of 55.9 kDa

This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]

Uniprot ID:P01730
Formulation & Reconstitution:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Usage:Research use only

Related Products