Biotinylated Human CD4 full length protein-synthetic nanodisc (HDFP759)
- SKU:
- HDFP759
- Size:
- 10μg
- Target:
- CD4
- Tag:
- Biotinylated, C-Flag&Avi Tag
- Expression Host:
- HEK293
- Conjugate:
- Biotinylated
Description
| Product Name: | Biotinylated Nanodisc Human CD4 Protein |
| SKU: | HDFP759 |
| Size: | 10μg |
| Target: | CD4 |
| Tag: | Biotinylated, C-Flag&Avi Tag |
| Expression Host: | HEK293 |
| Conjugate: | Biotinylated |
| Synonyms: | T4; IMD79; Leu-3; OKT4D; CD4mut |
| Protein Families: | Transmembrane. |
| Protein Description: | Biotinylated Human CD4 full length protein-synthetic nanodisc |
| Protein Pathways: | Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway. |
| Molecular Weight: | The human full length CD4 Protein has a MW of 55.9 kDa |
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
| Uniprot ID: | P01730 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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