The Biotinylated Anti-Trop2 Antibody (HDLA036) is a valuable tool for researchers studying Trop2, a cell surface protein associated with cancer. This antibody, produced in-house, is highly specific for Trop2 and has been validated for use in immunohistochemistry and flow cytometry applications. By binding to Trop2, this antibody enables the detection and analysis of Trop2 expression in various cell types, offering insights into its role in cancer development and progression.Trop2, also known as tumor-associated calcium signal transducer 2, is frequently overexpressed in cancer cells and has been implicated in promoting tumor growth, metastasis, and resistance to therapy.
Understanding the function of Trop2 is crucial for developing targeted therapies that can effectively treat Trop2-positive cancers. This antibody provides researchers with a reliable tool for investigating the role of Trop2 in cancer biology and identifying potential therapeutic targets for precision medicine approaches.
SKU:
HDLA036
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM74
Synonyms:
TACSTD2, GA733-1, M1S1, TROP2
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.