The Biotinylated Anti-Mesothelin Antibody (HDLA033) is a valuable tool for researchers studying mesothelin, a cell surface glycoprotein that is overexpressed in various cancers, particularly mesothelioma and ovarian cancer. This antibody, developed by Assay Genie, is specifically designed for use in immunohistochemistry and other laboratory techniques to detect mesothelin expression.Mesothelin is a promising target for cancer therapy due to its selective expression in tumor cells and limited distribution in normal tissues. The Biotinylated Anti-Mesothelin Antibody enables precise visualization of mesothelin in tissue samples, allowing researchers to study its role in cancer progression and its potential as a diagnostic or therapeutic target.
This antibody is highly specific and sensitive, providing reliable results in detecting mesothelin expression with minimal background noise. Its biotinylated form allows for easy detection using avidin-biotin complex methods, making it suitable for a wide range of experimental settings.Overall, the Biotinylated Anti-Mesothelin Antibody is a valuable tool for researchers interested in exploring the role of mesothelin in cancer biology and developing novel strategies for cancer diagnosis and treatment.
SKU:
HDLA033
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM71
Synonyms:
MSLN, Mesothelin, MPF
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
