The Biotinylated Anti-CD28 Antibody (HDLA027) is a powerful tool for researchers studying CD28, a key co-stimulatory molecule that plays a critical role in T cell activation and immune responses. This antibody, optimized for use in a variety of applications, including flow cytometry and immunohistochemistry, is highly specific for human CD28 and provides reliable detection and analysis in various sample types.CD28, a member of the immunoglobulin superfamily, is essential for T cell activation and proliferation, making it an attractive target for research in immunology and autoimmune diseases. Its interaction with ligands like CD80 and CD86 on antigen-presenting cells is vital for initiating and regulating immune responses.
The Biotinylated Anti-CD28 Antibody (HDLA027) enables precise detection of CD28 expression and localization in different cell populations, offering insights into T cell function and immune regulation.By understanding the role of CD28 in immune signaling pathways, researchers can gain valuable insights into autoimmune disorders, infectious diseases, and cancer immunotherapy. The Biotinylated Anti-CD28 Antibody (HDLA027) provides a reliable tool for investigating the function and regulation of CD28 in various experimental settings, advancing our knowledge of immune responses and paving the way for novel therapeutic interventions.
SKU:
HDLA027
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM64
Synonyms:
CD28, Tp44
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
