The Biotinylated Anti-CD138 Antibody (HDLA019) is a powerful tool for research involving CD138, a cell surface glycoprotein commonly found on plasma cells. This antibody is designed for use in various applications, including immunohistochemistry, immunofluorescence, and flow cytometry. This antibody is biotinylated, allowing for easy detection and analysis of CD138 expression in different tissues and cell types. Its high specificity and sensitivity make it ideal for studying the role of CD138 in diseases such as multiple myeloma, where abnormal plasma cells overexpress this protein.
Furthermore, the Biotinylated Anti-CD138 Antibody (HDLA019) has been validated for use in various sample types, including human samples, making it a versatile tool for researchers in the fields of oncology, hematology, and immunology. Understanding the expression and function of CD138 is crucial for developing targeted therapies for diseases involving plasma cells.
Product Code:
HDLA019
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM56
Synonyms:
SDC1, Syndecan-1, CD138, SYND1, SDC
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
Syndecan-1 (SYND1 or SDC1) is also known as CD antigen CD138, is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 / SDC1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a useful marker for plasma cells, but only if the cells tested are already known to be derived from blood.
