The Biotinylated Anti-CD138 Antibody (HDLA011) is a valuable tool for research involving CD138, a cell surface protein highly expressed on plasma cells. The antibody, conjugated with biotin for easy detection, is raised in rabbits and highly reactive with human samples. It has been validated for use in various applications, including Flow Cytometry and Immunohistochemistry.CD138, also known as Syndecan-1, is a key marker for plasma cells and is involved in cell adhesion and migration. Its high expression on plasma cells makes it a useful target for studies in immunology, oncology, and inflammation.
This antibody enables the specific detection and analysis of CD138 protein expression in different cell types, aiding in the understanding of its role in various diseases and conditions.Overall, the Biotinylated Anti-CD138 Antibody (HDLA011) is a reliable tool for researchers aiming to study CD138 expression and function in the context of cancer, autoimmune disorders, and other immune-related conditions. Its versatility and specificity make it a valuable asset for research in the fields of immunology and oncology.
Product Code:
HDLA011
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM46
Synonyms:
SDC1, Syndecan-1, CD138, SYND1, SDC
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
Syndecan-1 (SYND1 or SDC1) is also known as CD antigen CD138, is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 / SDC1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a useful marker for plasma cells, but only if the cells tested are already known to be derived from blood.
