The Biotinylated Anti-CD138 Antibody (HDLA010) is a valuable tool for researchers studying CD138, a cell surface protein also known as syndecan-1. This antibody, generated in-house using high-quality materials, is specifically designed to detect and analyze CD138 in various cell types, particularly in the context of immunology and cancer research.CD138 is a key marker for plasma cells and has been linked to multiple myeloma, a type of blood cancer. By targeting CD138 with this biotinylated antibody, researchers can gain insights into the role of CD138 in disease progression and immune function.
The biotinylated format allows for easy detection using streptavidin-based detection systems, making it suitable for a variety of applications such as immunohistochemistry and flow cytometry.By utilizing the Biotinylated Anti-CD138 Antibody (HDLA010), researchers can further our understanding of CD138 biology and potentially pave the way for the development of targeted therapies for diseases associated with CD138 dysregulation.
SKU:
HDLA010
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM45
Synonyms:
SDC1, Syndecan-1, CD138, SYND1, SDC
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
Syndecan-1 (SYND1 or SDC1) is also known as CD antigen CD138, is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 / SDC1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a useful marker for plasma cells, but only if the cells tested are already known to be derived from blood.
