The Biotinylated Anti-BTN3A1 Antibody (HDLA056) is a valuable tool for research involving BTN3A1, a cell surface protein with important roles in immune regulation and cancer biology. This antibody, generated using high-quality reagents and stringent validation protocols, is specially designed for use in various applications such as Western blotting and immunohistochemistry.BTN3A1, also known as Butyrophilin subfamily 3 member A1, is involved in immune responses and has been implicated in the activation of γδ T cells, which play crucial roles in antitumor immunity. The Biotinylated Anti-BTN3A1 Antibody specifically recognizes BTN3A1, allowing for precise detection and analysis of this protein in various biological samples.
This makes it an ideal tool for researchers investigating the roles of BTN3A1 in immune regulation, cancer progression, and potential therapeutic interventions.By providing insights into the function and expression of BTN3A1, this antibody contributes to advancing our understanding of immune responses and cancer biology. Its high specificity and sensitivity make it a valuable resource for studies aiming to uncover the mechanisms underlying immune dysregulation in diseases like cancer and autoimmune disorders.
SKU:
HDLA056
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM94
Synonyms:
BTN3A1, BTF5, CD277, BTN3.1, BT3.1
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each.
