The Biotinylated Anti-BCMA Antibody (HDLA001) is a powerful tool for studying B-cell maturation antigen (BCMA) in various research applications. BCMA is a cell surface receptor that plays a crucial role in the survival and function of plasma cells, making it a key target in cancer immunotherapy, particularly in multiple myeloma.This antibody, created through biotinylation for enhanced detection and quantification, is highly specific for BCMA, allowing for accurate and reliable results in experiments such as immunohistochemistry and flow cytometry.
Its high affinity and sensitivity make it an ideal choice for researchers investigating BCMA expression and functionality in cancer biology and immunology.Using the Biotinylated Anti-BCMA Antibody (HDLA001) provides a valuable tool for gaining insights into the role of BCMA in disease progression and therapeutic interventions, paving the way for advancements in precision medicine and targeted therapies for BCMA-expressing cancers.
Product Code:
HDLA001
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM16
Synonyms:
TNFRSF17
Applications:
ELISA, Flow Cyt
Recommended Dilution:
Flow Cyt 1:100; IP 1:30
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
