The Biotinylated Anti-ACE2 Antibody (HDLA013) is a valuable tool for researchers studying ACE2, a key receptor involved in viral entry and immunity regulation. This antibody, generated using high-quality biotin, is highly specific for human ACE2 samples and is suitable for various applications such as immunohistochemistry and flow cytometry.ACE2, also known as angiotensin-converting enzyme 2, plays a crucial role in regulating blood pressure and cardiovascular function, as well as serving as the entry point for viruses like SARS-CoV-2. By targeting ACE2 with this biotinylated antibody, researchers can effectively detect and analyze ACE2 expression in different cell types and tissues, aiding in the understanding of viral infections and immune responses.
The importance of ACE2 in viral pathogenesis and immune modulation makes this antibody an essential tool for studies on infectious diseases, respiratory disorders, and inflammation. With its high specificity and versatility, the Biotinylated Anti-ACE2 Antibody (HDLA013) is a valuable asset for researchers seeking to uncover the mechanisms underlying viral infections and develop potential therapeutic strategies.
SKU:
HDLA013
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM48
Synonyms:
ACE-2, ACEH, ACE2
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
