The Biotinylated Anti-2B4 Antibody (HDLA031) is a valuable tool for researchers studying the 2B4 protein, a cell surface receptor involved in immune cell signaling. This antibody, produced in-house, has been validated for use in various applications, including immunoprecipitation and flow cytometry, and is highly specific for human 2B4.The 2B4 protein, also known as CD244, is expressed on natural killer cells, cytotoxic T cells, and some B cells, where it plays a role in regulating immune responses. By targeting 2B4 with this biotinylated antibody, researchers can study the interactions and functions of this protein in various cell types, providing valuable insights into immune system function and potential therapeutic targets for immune-related disorders.
Whether studying immune cell activation, target cell recognition, or immune cell-mediated cytotoxicity, the Biotinylated Anti-2B4 Antibody (HDLA031) is a versatile tool that can enhance research efforts in immunology, cancer biology, and other fields related to immune system regulation.
SKU:
HDLA031
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM69
Synonyms:
CD244,2B4,SLAMF4,NKR2B4,NAIL,h2B4
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
