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Biotin Anti-Mouse TCR ?/δ Antibody [GL3] (AGEL3298)

SKU:
AGEL3298
€149 - €539
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Description

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Biotin Anti-Mouse TCR γ/δ Antibody [GL3]

The Anti-Mouse TCR Antibody (GL3) offered by Assaygenie is a high-quality research tool designed for the study of T-cell receptor (TCR) signaling in mouse models. This monoclonal antibody specifically targets and detects the TCR beta chain, an essential component of the TCR complex involved in antigen recognition and T-cell activation.Developed for use in various experimental applications, the Anti-Mouse TCR Antibody (GL3) is ideal for immunofluorescence, flow cytometry, and immunohistochemistry studies. Its high specificity and sensitivity ensure reliable and reproducible results, making it a valuable tool for researchers investigating TCR-mediated immune responses, T-cell development, and immune surveillance mechanisms in mouse models.

By targeting the TCR beta chain, the Anti-Mouse TCR Antibody (GL3) enables precise detection and analysis of TCR-expressing cells in different tissues and experimental conditions. This antibody's versatility and robust performance make it a trusted reagent for immunology research, offering valuable insights into T-cell function, immune activation, and the adaptive immune response in mouse models.

Product Title:Biotin Anti-Mouse TCR γ/δ Antibody [GL3]
SKU:AGEL3298
Size:25µg, 100µg
Clone No:GL3
Synonyms:T cell receptor γ/δ;
Host Species:Syrian Hamster
Reactivity:Human;Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Biotin Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:Q96E93 O88713
Gene ID:110066,110067
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, which is involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. γ/δ TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8- although some are CD8+. T cells expressing the γ/δ TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation.

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