The Biotin Anti-Mouse H-2 Antibody (M1/42) offered by AssayGenie is a highly specific and reliable tool for researchers working with mouse models and studying immune responses. This antibody is designed to target the H-2 complex, a critical component of the mouse immune system involved in antigen presentation and immune recognition.The Biotin Anti-Mouse H-2 Antibody (M1/42) is produced using biotin conjugation technology, which allows for easy and efficient detection in a variety of assays, including immunohistochemistry and flow cytometry. Its high specificity for the H-2 complex ensures accurate and reproducible results in experiments investigating immune cell activation, transplantation, and immune system function in mouse models.
Researchers in immunology, transplantation biology, and vaccine development can benefit from the reliable performance and versatility of the Biotin Anti-Mouse H-2 Antibody (M1/42). Its application extends to a wide range of research areas where understanding immune responses in mouse models is crucial, making it an essential tool for advancing scientific knowledge and developing new therapeutic strategies.
Product Title:
Biotin Anti-Mouse H-2 Antibody [M1/42]
SKU:
AGEL2409
Size:
25µg, 100µg
Clone No:
M1/42
Synonyms:
Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Biotin Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Biotin
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Gene ID:
111364
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.