The Biotin Anti-Mouse CD5 Antibody (53-7.3) from AssayGenie is a high-quality research tool designed for detecting and analyzing CD5, a cell surface protein known for its role in regulating immune responses. This antibody, specifically developed for use with mouse samples, is raised in biotin and is ideal for applications such as immunohistochemistry and flow cytometry.CD5 is a crucial marker for T and B cell development and function, making this antibody essential for studies in immunology, lymphocyte signaling, and autoimmunity.
By targeting CD5, researchers can investigate the expression and localization of this protein in various cell types, aiding in the understanding of immune system dynamics and potential therapeutic targets.Utilizing the Biotin Anti-Mouse CD5 Antibody (53-7.3) from AssayGenie opens up opportunities for in-depth research into immune system regulation and lymphocyte behavior, offering valuable insights into immune-related disorders and potential therapeutic interventions.
Product Title:
Biotin Anti-Mouse CD5 Antibody [53-7.3]
SKU:
AGEL3334
Size:
25µg, 100µg
Clone No:
53-7.3
Synonyms:
Ly-1;Lyt-1;Lymphocyte antigen 1;CD5;Cd5;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Biotin Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Biotin
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P13379
Gene ID:
12507
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD protein, also known as Lyt-1, Ly-1, T1, Tp67, or Ly-12. It is a member of the scavenger receptor cysteine-rich protein superfamily (SRCR) and primarily expressed on thymocytes, T cells, and B-1 cells. Although mature α/β T cells express high levels of CD5, very few γ/δ T cells express this antigen. The interaction of CD5 with CD72, gp35-37, TCR, or BCR is involved in T and B cell activation.