The Biotin Anti-Mouse CD31 Antibody (390) from Assay Genie is a powerful tool for researchers studying murine immune responses and vascular biology. This highly specific antibody, raised against CD31, also known as platelet endothelial cell adhesion molecule (PECAM-1), is ideal for various applications in immunology and angiogenesis research.CD31 is a transmembrane glycoprotein involved in cell adhesion, migration, and signaling within the immune system and blood vessels. The Biotin Anti-Mouse CD31 Antibody (390) recognizes this critical marker with high affinity, enabling precise detection and analysis in mouse tissue samples.
Whether investigating endothelial cell function, leukocyte trafficking, or vascular development, this antibody provides accurate and reliable results in techniques such as immunohistochemistry and flow cytometry.By targeting CD31, researchers can gain insights into the complex interplay between immune cells, endothelial cells, and the microenvironment in various physiological and pathological conditions. The versatility and specificity of the Biotin Anti-Mouse CD31 Antibody (390) make it an indispensable tool for unraveling the intricacies of immune regulation and vascular biology in preclinical and translational studies.
Product Title:
Biotin Anti-Mouse CD31 Antibody [390]
SKU:
AGEL3331
Size:
25µg, 100µg
Clone No:
390
Synonyms:
Pecam; Pecam-1;PECAM-1;CD31;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Biotin Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Biotin
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
Q08481
Gene ID:
18613
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.