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Biotin Anti-Human CD40 Antibody [G28.5] (AGEL3380)

SKU:
AGEL3380
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
G28.5
Conjugation:
Biotin
€149 - €219
Frequently bought together:

Description

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Biotin Anti-Human CD40 Antibody [G28.5]

The Biotin Anti-Human CD40 Antibody (G28-5) offered by AssayGenie is a highly specific and reliable tool for researchers studying CD40, a key cell surface receptor involved in immune responses and signaling. This antibody, optimized for use with human samples, is produced using biotin conjugation for enhanced detection capabilities in various experimental methods.CD40 is a crucial molecule found on the surface of immune cells, particularly B cells, dendritic cells, and macrophages. It plays a fundamental role in regulating immune responses, including antibody production, inflammation, and the activation of T cells. The Biotin Anti-Human CD40 Antibody (G28-5) binds specifically to CD40, allowing for accurate detection and characterization of this important receptor in diverse cell types and experimental settings.

Researchers focusing on immunology, inflammation, and vaccine development will find this antibody particularly valuable in studying the intricate mechanisms governed by CD40 signaling. Its high specificity and sensitivity make it an essential tool for exploring the intricate interplay between immune cells and their responses to external stimuli, paving the way for new insights into immune-related diseases and potential therapeutic interventions.For reliable and accurate detection of CD40 in human samples and cell lines, the Biotin Anti-Human CD40 Antibody (G28-5) from AssayGenie is an indispensable resource for advancing research in immunology, vaccine development, and related fields.

Product Title:Biotin Anti-Human CD40 Antibody [G28.5]
SKU:AGEL3380
Size:25µg, 100µg
Clone No:G28.5
Synonyms:Bp50;CDw40;CD40L receptor;TNFRSF5;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Biotin Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P25942
Gene ID:958
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).

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