The BIN3 Polyclonal Antibody (CAB15478) is dedicated to research on BIN3, a protein involved in various cellular processes such as cell growth and division. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blotting techniques. By targeting the BIN3 protein, this antibody allows for precise detection and analysis in a variety of cells, making it a valuable tool for studies in cell biology and cancer research.BIN3 is known to play a pivotal role in cellular functions, including cell cycle regulation and apoptosis. Its involvement in key processes makes it a promising target for investigations into cancer development and progression.
Understanding the functions and mechanisms of BIN3 is essential for unraveling its potential contributions to disease pathogenesis and identifying novel therapeutic strategies for cancer treatment.Overall, the BIN3 Polyclonal Antibody (CAB15478) is a reliable reagent for researchers interested in exploring the roles of BIN3 in cellular processes and cancer biology. Its high specificity and sensitivity make it a valuable asset in advancing our understanding of BIN3 function and its implications in disease contexts.
Product Name:
BIN3 Rabbit Polyclonal Antibody
SKU:
CAB15478
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human BIN3 (NP_061158.1).
The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.
Purification Method:
Affinity purification
Gene ID:
55909
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using BIN3 Rabbit pAb (CAB15478) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
