The BICD2 Polyclonal Antibody (CAB10292) is a valuable tool for researchers studying BICD2, a protein involved in the regulation of intracellular transport and organization of the Golgi apparatus. This antibody, raised in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. It specifically binds to the BICD2 protein, allowing for detection and analysis in various cell types.BICD2 is known to play a crucial role in cellular processes such as vesicle trafficking and organelle positioning, making it a key target for research in cell biology and neurodegenerative diseases.
By understanding the function of BICD2, researchers can gain insights into how disruptions in intracellular transport contribute to disease pathology, particularly in conditions like amyotrophic lateral sclerosis (ALS) and hereditary spastic paraplegia (HSP).With its ability to detect BICD2 in human samples, the CAB10292 antibody is an essential tool for researchers investigating the mechanisms underlying intracellular transport and Golgi organization. Its use in Western blot applications makes it a versatile antibody for studies aiming to uncover the roles of BICD2 in normal cellular function and disease processes.
Product Name:
BICD2 Rabbit Polyclonal Antibody
SKU:
CAB10292
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 440-620 of human BICD2 (NP_001003800.1).
This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described.
Purification Method:
Affinity purification
Gene ID:
23299
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using BICD2 antibody (CAB10292) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
