The BHMT Polyclonal Antibody (CAB1216) offered by Assay Genie is an essential tool for researchers studying the Betaine-homocysteine methyltransferase (BHMT) protein. BHMT is an enzyme involved in the metabolism of homocysteine and its dysregulation has been linked to various medical conditions such as cardiovascular disease and liver disorders. This polyclonal antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the BHMT protein, researchers can detect and analyze its expression in a variety of cell types, making it an ideal choice for studies in metabolism, cardiovascular health, and liver function.
Understanding the role of BHMT in homocysteine metabolism is crucial for developing targeted therapies for conditions associated with its dysregulation. The BHMT Polyclonal Antibody (CAB1216) provides a reliable tool for researchers to further investigate the functions and mechanisms of BHMT in health and disease.
Product Name:
BHMT Rabbit Polyclonal Antibody
SKU:
CAB1216
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 177-406 of human BHMT (NP_001704.2).
This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.
Purification Method:
Affinity purification
Gene ID:
635
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat liver, using BHMT Rabbit pAb antibody (CAB1216) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
